个人简介
姓名：陈鸿策
学历：博士研究生
职称：特聘副研究员
研究方向：生物物理学、细胞生物学
联系电话：135 4346 4673
电子邮箱：hcchen2009@126.com
通讯地址：广州天河区中山大道西55号华南师范大学生物光子学研究院（510631）
教育经历：
2022.7 -至今 华南师范大学 博士后
2019.9-2022.7 华南师范大学 博士研究生
2016.9-2019.7 广东药科大学 硕士研究生
2009.9-2013.7 河南科技大学 本科
研究方向：
1. 生物物理学，细胞生物学；
2.荧光共振能量转移(FRET)技术的应用；
3. 肿瘤的信号网络调控，抗肿瘤分子机制的研究。
发表论文：
[1]Chen Hongce, Sun Beini, Sun Han, Xu Lingjun, Wu Guihao, Tu Zhuang, Cheng Xuecheng, Fan Xuhong, Mai Zihao, Tang Qiling, Wang Xiaoping*, Chen Tongsheng*. Bak instead of Bax plays a key role in metformin-induced apoptosis in HCT116 cells. Cell Death Discov. 2021 Nov 22;7(1):363. doi: 10.1038/s41420-021-00755-y.
[2]Chen Hongce, Rui Wen, You Siyuan, Chen Hongyuan *. Evaluation of the anti-cervical cancer effect of a prodrug ：CBZ-AAN-DOX with hypoxic cell culture and tumor-bearing zebrafish models. Exp Cell Res. 2020 Jun 1;391(1):111980 .
[3]Chen Hongce, Fu Wuyu, Chen Hongyuan, Rui Wen*. Magnolol attenuates the inflammation and enhances phagocytosis through the activation of MAPK, NF-κB signal pathways in vitro and in vivo. Molecular Immunology, 2019, 105:96.
[4]Tang Qiling, Chen Hongce, Mai Zihao, Sun Han, Xu Lingjun, Wu Guihao, Tu Zhuang, Cheng Xuecheng, Wang Xiaoping*, Chen Tongsheng*. Bim- and Bax-mediated mitochondrial pathway dominates abivertinib-induced apoptosis and ferroptosis. Free Radic Biol Med. 2022 Feb 20;180:198-209. doi: 10.1016/j.freeradbiomed.2022.01.013.
[5]Liu Zhi, Luo Zewei, Chen Hongce, Yin Ao, Sun Han, Zhuang Zhengfei*, Chen Tongsheng. Optical section structured illumination-based Förster resonance energy transfer imaging. Cytometry A. 2022 Mar;101(3):264-272. doi: 10.1002/cyto.a.24500.
[6]Yin Ao, Sun Han, Chen Hongce, Liu Zhi, Tang Qiling, Yuan Ye, Tu Zhuang, Zhuang Zhengfe*, Chen Tongsheng. Measuring calibration factors by imaging a dish of cells expressing different tandem constructs plasmids. Cytometry A. 2021 Jun;99(6):632-640. doi: 10.1002/cyto.a.24316.
[7]Sun Han, Yin Ao, Gao Lu, Chen Hongce, Tang Qiling, Yuan Ye, Liu Zhi, Zhuang Zhengfei*, Chen Tongsheng.Measuring System Calibration Factors by Unmixing the Excitation–Emission Spectra of One Dish of Cells. Microsc Microanal.2021 Dec 27:1-8. doi: 10.1017/S1431927621012642.
[8]Wu Ge, Tu Zhuang, Yang Fangfang, Mai Zihao, Chen Hongce, Tang Qiling, Ye Xianxin, Wang Kunhao, Wang Xiaoping*, Chen Tongsheng*. Evaluating the inhibitory priority of Bcl-xL to Bad, tBid and Bax by using live-cell imaging assay. Cytometry A. 2021 Nov;99(11):1091-1101. doi: 10.1002/cyto.a.24351.
[9]Sun Han, Zhang Chenshuang, Yuan Ye, Gao Lu, Zhai Shixian, Chen Hongce, Tang Qiling, Zhuang Zhengfei*, Chen Tongsheng*. Automated ExEm-spFRET Microscope. Microsc Microanal. 2022 Feb 21:1-8. doi: 10.1017/S1431927621013891.
[10]Guihao Wu , Cifeng Zhang , Lingjun Xu , Hongce Chen , Xuhong Fan , Beini Sun 2, Qiling Tang , Yongtong Zhan , Tongsheng Chen , Xiaoping Wang. BAK plays a key role in A-1331852-induced apoptosis in senescent chondrocytes. Biochem Biophys Res Commun. 2022 Jun 18;609:93-99. doi: 10.1016/j.bbrc.2022.03.155.