个人简介
姓名：孙贝妮
学历：博士研究生
职称：特聘副研究员
研究方向：生物物理学、细胞生物学、药理学
电子邮箱：838143468@qq.com
通讯地址：广州天河区中山大道西55号华南师范大学生物光子学研究院（510631）
教育经历：
2023.7-至今 华南师范大学 博士后
2020.9-2023.7 华南师范大学 博士研究生
2017.9-2020.7 黑龙江大学 硕士研究生
2013.9-2017.7 黑龙江大学 本科
研究方向：
1. 生物物理学，细胞生物学，药理学；
2. 荧光共振能量转移(FRET)技术的应用；
3. 肿瘤的信号网络调控，抗肿瘤分子机制的研究；
4. 高内涵药物筛选。
发表论文：
[1] Beini Sun, Hongce Chen, et al. Regorafenib induces Bim-mediated intrinsic apoptosis by blocking AKT-mediated FOXO3a nuclear export. Cell Death Discov. 2023; 9(1): 37.
[2] Yuhong Lin, Beini Sun, et al. Enhanced Immune Responses to Mucosa by Functionalized Chitosan-Based Composite Nanoparticles as a Vaccine Adjuvant for Intranasal Delivery. ACS Appl Mater Interfaces. 2022; 14(47): 52691-52701.
[3] Juzuo Zhang#, Beini Sun#, et al. Screening and surveillance of multiple solid tumours using plasma placental-like chondroitin sulfate A (pl-CSA). Int J Med Sci. 2020; 17(2): 161-169.
[4] Kai Zhao, Beini Sun, et al. Intranasal immunization with O-2'-Hydroxypropyl trimethyl ammonium chloride chitosan nanoparticles loaded with Newcastle disease virus DNA vaccine enhances mucosal immune response in chickens. J Nanobiotechnology. 2021 ;19(1): 240.
[5] Zhuo Zheng, Beini Sun,et al. Unsupervised deep learning of bright-field images for apoptotic cellclassification. Signal, Image and Video Processing. 2023. doi.org/10.1007/s11760-023-02592-1
[6] Hongce Chen, Beini Sun, et al. Bak instead of Bax plays a key role in metformin-induced apoptosis s in HCT116 cells. Cell Death Discov. 2021; 7(1): 363.
[7] Beini Sun, et al. Sun B, Yu S, Zhao D, Guo S, Wang X, Zhao K. Polysaccharides as vaccine adjuvants. Vaccine. 2018; 36(35): 5226-5234.
[8] Shuo Wang, Min Hu, Beini Sun, et al. Dependence of ghost on the incident light angle into dichroic mirror. J Biophotonics. 2023; 16(11): e202300190.
[9] Xin Chen#, Tailang Yin#, Baozhen Zhang#, Beini Sun, et al. Inhibitory effects of brusatol delivered using glycosaminoglycan‑placental chondroitin sulfate A‑modified nanoparticles on the proliferation, migration and invasion of cancer cells. Int J Mol Med. 2020; 46(2): 817-827.
[10] Zhilong Chen, Juzuo Zhang, Anwen Yuan, Jinyu Han, Lunbo Tan, Zhuoqun Zhou, Huashan Zhao,Rui Su, Binbin Huang, Baobei Wang, Beini Sun, et al. R-spondin3 promotes the tumor growth of choriocarcinoma JEG-3 cells. Am J Physiol Cell Physiol. 2020; 318(3): C664-C674.
[11] Kai Zhao, Guogang Cheng, Beini Sun, et al. Targeting delivery of partial VAR2CSA peptide guided N-2-Hydroxypropyl trimethyl ammonium chloride chitosan nanoparticles for multiple cancer types. Mater Sci Eng C Mater Biol Appl. 2020; 106: 110171.
[12] Guihao Wu, Cifeng Zhang, Lingjun Xu, Hongce Chen, Xuhong Fan, Beini Sun, et al. BAK plays a key role in A-1331852-induced apoptosis in senescent chondrocytes. Biophys Res Commun. 2022; 609: 93-99.
[13] Zihao Mai, Han Sun, Fangfang Yang, Mengyan Du, Xuecheng Cheng, Hongce Chen, Beini Sun, et al. Bad is essential for Bcl-xL-enhanced Bax shuttling between mitochondria and cytosol. Int J Biochem Cell Biol. 2023; 155: 106359.